1,2,4-Piperazinetricarboxylic acid, 1-(1,1-dimethylethyl) 4-(9H-fluoren-9-ylmethyl) ester, (2R)- - Names and Identifiers
Name | (2R)-1-(tert-butoxycarbonyl)-4-[(9H-fluoren-9-ylmethoxy)carbonyl]piperazine-2-carboxylic acid
|
Synonyms | (R)-N1-Boc-N4-Fmoc-piperazine-2-carboxylic acid (R)-1-N-Boc-4-N-Fmoc-2-Piperazine carboxylic acid 1-TERT-BUTYL 4-(9-H-FLUOREN-9-YLMETHYL) HYDROGEN (2R)-PIPERAZINE-1,2,4-TRICARBOXYLATE (2R)-1-(tert-butoxycarbonyl)-4-[(9H-fluoren-9-ylmethoxy)carbonyl]piperazine-2-carboxylic acid (2R)-1-(tert-Butoxycarbonyl)-4-[(9H-fluoren-9-ylmethoxy)carbonyl]piperazine-2-carboxylic acid (R)-1-N-tert-Butoxycarbonyl-4-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-2-piperazine carboxylic acid 1,2,4-Piperazinetricarboxylic acid, 1-(1,1-dimethylethyl) 4-(9H-fluoren-9-ylmethyl) ester, (2R)- (2R)-1-[(tert-butoxy)carbonyl]-4-{[(9H-fluoren-9-yl)methoxy]carbonyl}piperazine-2-carboxylic acid
|
CAS | 209593-18-0
|
InChI | InChI=1/C25H28N2O6/c1-25(2,3)33-24(31)27-13-12-26(14-21(27)22(28)29)23(30)32-15-20-18-10-6-4-8-16(18)17-9-5-7-11-19(17)20/h4-11,20-21H,12-15H2,1-3H3,(H,28,29)/t21-/m1/s1 |
1,2,4-Piperazinetricarboxylic acid, 1-(1,1-dimethylethyl) 4-(9H-fluoren-9-ylmethyl) ester, (2R)- - Physico-chemical Properties
Molecular Formula | C25H28N2O6
|
Molar Mass | 452.5 |
Density | 1.292g/cm3 |
Boling Point | 624.4°C at 760 mmHg |
Flash Point | 331.4°C |
Vapor Presure | 1.88E-16mmHg at 25°C |
Storage Condition | 2-8°C |
Refractive Index | 1.597 |
1,2,4-Piperazinetricarboxylic acid, 1-(1,1-dimethylethyl) 4-(9H-fluoren-9-ylmethyl) ester, (2R)- - Introduction
(2R)-1-(tert-butoxycarbonyl)-4-[(9H-fluoren-9-ylmethoxy)carbonyl]piperazine-2-carboxylic acid is a compound, the following is its properties, use, preparation and safety information:
Nature:
(2R)-1-(tert-butoxycarbonyl)-4-[(9H-fluoren-9-ylmethoxy)carbonyl]piperazine-2-carboxylic acid is an organic compound with a protecting group. Its chemical formula is C21H21NO6 and its molecular weight is 383.4g/mol. This compound is a solid with a white to yellowish color at room temperature. It is soluble in organic solvents.
Use:
(2R)-1-(tert-butoxycarbonyl)-4-[(9H-fluoren-9-ylmethoxy)carbonyl]piperazine-2-carboxylic acid is a common intermediate in organic synthesis. Its protecting groups can protect other functional groups in chemical reactions to prevent unwanted reactions. This makes it widely used in the field of pharmaceutical and organic chemistry synthesis.
Method:
The preparation of (2R)-1-(tert-butoxycarbonyl)-4-[(9H-fluoren-9-ylmethoxy)carbonyl]piperazine-2-carboxylic acid can be achieved by chemical synthesis. A common synthetic method is to react piperazine carboxylic acid with an appropriate protecting group (e. G. Boc Group and Fmoc group) to give the desired product. Specific preparation methods can be found in the literature of organic synthesis.
Safety Information:
When using (2R)-1-(tert-butoxycarbonyl)-4-[(9H-fluoren-9-ylmethoxy)carbonyl]piperazine-2-carboxylic acid, pay attention to the following safety precautions: must comply with Good Laboratory Practices, avoid direct contact with skin and eyes, use ventilation equipment to maintain proper ventilation, avoid inhaling gas or dust, if there is poor breathing, it should be removed to fresh air immediately. In addition, the substance should be stored in a sealed container, away from high temperatures and sources of fire. Detailed safety information can be found in the relevant safety data sheet.
Last Update:2024-04-10 22:29:15